Joint Research

Clinical Artificial Intelligence-based Diagnostics (CAIDX)

Project summary

Digitalisation is increasing rapidly across all sectors including healthcare. This can result in positive effects by increasing the healthcare sector's reactivity and resilience (increasing speed and accuracy of diagnostics, optimising resources).

AI and data driven diagnostics tools are being intensively developed for applications in the healthcare sector, but the uptake is difficult for several reasons:

  • Hospitals/clinicians see AI as a black box and do not understand the logic behind the algorithms used;
  • The industry does not necessarily grasp clinical needs, so they provide tools that are not meeting requirements of users;
  • Hospitals do not have the expertise to acquire and contract those tools based on validated scientific data;
  • Hospitals need support in developing tools together with solution providers and secure implementation into existing IT platforms, linking with patients’ data and fitting them in the workflow;
  • Staff is not prepared for adopting the solutions or trained to use and make the best use of them.

CAIDX aims to create the conditions to facilitate the uptake of AI and data driven diagnostics tools for healthcare (and hospitals in particular) by focusing on co-development, contracting, acquisition and capacity building. By developing standard procedures for development, testing and implementation of such AI applications, our solutions will improve and accompany the cultural change necessary to unfold the potential of AI in the healthcare sector.

Programme: Interreg Baltic Sea Region Programme 2021-2027

Implementation period: January 2023 – December 2025

Budget: 2.91€ Million in total 

Lead partner: The Innovation Clinic, Aalborg University Hospital, The North Denmark Region (DK)

Partners: 

  1. Wroclaw Technology Park (PL)
  2. BioCon Valley® GmbH (DE)
  3. Tartu BT Park OÜ (EE)
  4. Turku Science Park Ltd (FI)
  5. Lower Silesian Centre of Oncology, Pulmonology and Hematology (PL)
  6. Region Skane (SE)
  7. Innovation Skane (SE)
  8. Rostock University Medical Centre (DE)
  9. AUH Innovation, Aarhus University Hospital, Central Denmark Region (DK)
  10. Danish Life Science Cluster (DK)
  11. University of Rostock (DE)
  12. The Wellbeing Services County of Southwest Finland (FI)

https://interreg-baltic.eu/project/caidx/

Parkinson's disease (VALIDATE-PD)

A current study of both sites (Lund/Rostock) on motor and non-motor fluctuations in the late phase of Parkinson's disease (VALIDATE-PD).

Project Leaders: Per Odin (Lund), Alexander Storch (Rostock)

Parkinson’s disease (Subanalyses of CLaSP and NoMoFlu-PD studies)

Defining non-motor symptoms in Parkinson’s disease during the disease course.

Project Leaders: Per Odin (Lund), Alexander Storch (Rostock)

Application of single wrist-wearable accelerometry for objective motor diary assessment in fluctuating Parkinson's disease.

Löhle M, Timpka J, Bremer A, Khodakarami H, Gandor F, Horne M, Ebersbach G, Odin PStorch A.NPJ Digit Med. 2023 Oct 17;6(1):194. doi: 10.1038/s41746-023-00937-1.PMID: 37848531


A Novel Anthropomorphic Phantom Composed of Tissue-Equivalent Materials for Use in Experimental Radiotherapy: Design, Dosimetry and Biological Pilot Study.

Breslin T, Paino J, Wegner M, Engels E, Fiedler S, Forrester H, Rennau H, Bustillo J, Cameron M, Häusermann D, Hall C, Krause D, Hildebrandt G, Lerch M, Schültke E. Biomimetics (Basel). 2023 May 31;8(2):230. doi: 10.3390/biomimetics8020230. PMID: 37366825; PMCID: PMC10296262.


Objective Observer vs. Patient Motor State Assessments Using the PD Home Diary in Advanced Parkinson's Disease.

Timpka J, Löhle M, Bremer A, Christiansson S, Gandor F, Ebersbach G, Dahlström Ö, Iwarsson S, Nilsson MH, Storch A, Odin P.Front Neurol. 2022 Jul 12;13:935664. doi: 10.3389/fneur.2022.935664. eCollection 2022.PMID: 35903114


Validation of the PD home diary for assessment of motor fluctuations in advanced Parkinson's disease.

Löhle M, Bremer A, Gandor F, Timpka J, Odin P, Ebersbach G, Storch A.NPJ Parkinsons Dis. 2022 Jun 2;8(1):69. doi: 10.1038/s41531-022-00331-w.PMID: 35654835


Dopaminergic Effect on Non-Motor Symptoms in Late Stage Parkinson's Disease.

Rosqvist K, Odin P, Hagell P, Iwarsson S, Nilsson MH, Storch A. J Parkinsons Dis. 2018;8(3):409-420. doi: 10.3233/JPD-181380.PMID: 30056433


Disease stage dependency of motor and non-motor fluctuations in Parkinson's disease.

Storch A, Rosqvist K, Ebersbach G; NoMoFlu-PD Study Group, Odin P.J Neural Transm (Vienna). 2019 Jul;126(7):841-851. doi: 10.1007/s00702-019-02033-9. Epub 2019 Jun 19.PMID: 31218469

UNC Affiliation

United Neuroscience Campus Lund-Rostock (UNC), Rostock site

United Neuroscience Campus Lund-Rostock (UNC), Lund site